Why many people on amphetamine salts and kanna feel like they need higher initial doses

https://front-wiki.win/index.php/7_Practical_Fixes_When_Your_Kanna_Chew_Feels_Like_Nothing_(and_How_to_Rescue_That_Late-Night_Reddit_Regret)

People who take prescription amphetamine salts and also try kanna (Sceletium tortuosum) often report surprising early experiences: the stimulant feels muted or the kanna produces little effect until they bump up the dose