When picking or editing a gaming or anime PFP, focus on a clear silhouette and...

https://purepfp.com/why-bold-game-characters-remain-recognisable-in-tiny-profile-icons/

When picking or editing a gaming or anime PFP, focus on a clear silhouette and crop tightly around the face to keep it recognizable. Use a simple background with good contrast so the image doesn’t get lost when shrunk